Can liver disease be linked to heart failure? VCU study highlights liver-heart interaction

By Anne Dreyfuss
VCU C. Kenneth and Dianne Wright Center for Clinical and Translational Research

Virginia Commonwealth University researchers have collaborated on a clinical trial that identifies indicators for nonalcoholic fatty liver disease — a typically asymptomatic disease caused by fat buildup in the liver and the leading cause of liver disease in the United States.

Mohammad Siddiqui, M.D., an associate professor in the VCU School of Medicine, and researchers with expertise in cardiology, hepatology, and exercise physiology have been conducting research with a focus on the link between heart and liver damage. Their efforts have resulted in a study in which they draw a connection between patients with aggressive types of fatty liver disease and limitations in exercise capacity.

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Passion pays off: Sanyal to receive premier award in field of liver disease

By Polly Roberts
VCU School of Medicine

Headshot of Dr. Sanyal

In November 2018, Arun Sanyal, M.D., will accept the 2018 Distinguished Achievement Award from the American Association for the Study of Liver Diseases. The award signifies 30 years of research including 17 continuous years of National Institutes of Health funding, the development of therapeutics reducing liver disease across the globe, and countless international leadership roles and awards.

“This is the premier award in the field of liver disease and Dr. Sanyal is most deserving,” says Dean of Medicine Peter F. Buckley, M.D. “His work is the definition of translational medicine. Through his extraordinary commitment to research, teaching and patient care, and to always finding a better way, he has improved the standard of care for liver disease around the world.” Read More

Wright Center translational science classes inspire VCU cancer researcher

Headshot of Dr. Lathika Mohanraj
Lathika Mohanraj, Ph.D.

By Blake Belden
VCU Massey Cancer Center

Lathika Mohanraj, Ph.D., identifies genetic biomarkers that could aid in the early detection of patients at risk for complications from bone marrow transplantation, hematologic cancers and other malignancies.

Her mother, a breast cancer survivor, was diagnosed with the disease while Mohanraj was an undergrad student in India. Living through that experience solidified her passion to pursue a career in cancer research and treatment.

“Watching my mom go through it and going to the hospital and seeing the other cancer patients there — it was a lot for me to experience at an impressionable age,” Mohanraj said. “That triggered my interest, and from then on I knew that’s what I was going to do.” Read More

Interdisciplinary VCU research team provides clinical and diagnostic guidance for broken-heart syndrome

By Anne Dreyfuss
VCU C. Kenneth and Dianne Wright Center for Clinical and Translational Research

 

Infographic describing broken heart syndrome
Broken heart syndrome usually results from severe emotional or physical stress such as the death of a loved one. (Image courtesy of the Journal of the American College of Cardiology)

A team of cardiology and psychiatry specialists from Virginia Commonwealth University has authored a new comprehensive clinical review article in the Journal of the American College of Cardiology that summarizes the latest evidence-based diagnostic criteria and treatment strategies for Takotsubo cardiomyopathy, also known as broken-heart syndrome.

“Takotsubo cardiomyopathy is a recently recognized condition that is difficult to diagnose and treat,” said corresponding author Antonio Abbate, M.D., Ph.D. Abbate is a cardiology professor at VCU School of Medicine. He serves as associate director of the C. Kenneth and Dianne Wright Center for Clinical and Translational Research and as medical director of the Clinical Research Services unit. Read More